Cellular and Molecular Bioengineering - Poster Session D

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Presentations:

• 3:30 PM - 4:30 PM EST

  Optimizing Multiplexing of Antibodies for Immunocytochemistry
  

  Presenting Author: Dennis Ngo (he/him/his) – Johns Hopkins University

  Co-Author: Huan Ting Ong, PhD (she/her/hers) – Mechanobiology Institute at the National University of Singapore

  Primary Investigator: Jennifer L. Young – Mechanobiology Institute at the National University of Singapore
• 3:30 PM - 4:30 PM EST

  Optimizing the internalization of a peptide nanoplatform for Cas9 RNP delivery and gene editing
  

  Presenting Author: Alyson N. Schwartz (she/her/hers) – Clemson University

  Co-Author: Joseph LaValla (he/him/his) – Clemson University

  Co-Author: Audrey Wessinger (she/her/hers) – Clemson University

  Co-Author: Jessica Larsen, PhD – Clemson University Department of Chemical and Biomolecular Engineering

  Primary Investigator: Angela Alexander-Bryant, PhD – Clemson University
• 3:30 PM - 4:30 PM EST

  Optimizing the Physiology and Transduction Efficiency of Liver Organ-Tissue Equivalents to Study AAV-6 Gene Therapy Related Toxicity
  

  Presenting Author: Roma Desai (she/her/hers) – Johns Hopkins University

  Co-Author: Sarah Wachtman (she/her/hers) – Wake Forest Institute for Regenerative Medicine

  Co-Author: James Rice, PhD – Wake Forest Institute for Regenerative Medicine

  Co-Author: Anthony Atala, MD – Wake Forest Institute for Regenerative Medicine/Wake Forest School of Biomedical Engineering and Sciences

  Co-Author: Christopher D. Porada, PhD (he/him/his) – Wake Forest Institute for Regenerative Medicine

  Primary Investigator: Graça Almeida-Porada, MD, PhD (she/her/hers) – Wake Forest Institute for Regenerative Medicine
• 3:30 PM - 4:30 PM EST

  Optogenetic Control of RhoA Signaling in HeLa and 3T3 Cells
  

  Presenting Author: Kehinde Olawepo – Alabama A&M University

  Primary Investigator: Joel Boerckel, Ph.D. – University of Pennsylvania

  Co-Author: Erin Berlew, PhD – Department of Orthopaedic Surgery, University of Pennsylvania

  Co-Author: Paula Camacho Sierra, DVM, PhD – University of Pennsylvania
• 3:30 PM - 4:30 PM EST

  Orthogonally controlling the expression of the shell protein and assembly factors enables optimally controlled assembly of gas-filled protein nanostructures in heterologous hosts
  

  Presenting Author: Sumin Jeong (she/her/hers) – Rice University

  Co-Author: Zongru Li – Rice University

  Primary Investigator: George Lu, PhD (he/him/his) – Rice University
• 3:30 PM - 4:30 PM EST

  Paracrine Signaling by Distinct Adipose Tissue Depots Regulate Fibroblast-to-Myofibroblast Transition
  

  Presenting Author: Ryan W. Catlett (he/him/his) – University of Missouri-Columbia

  Co-Author: Yujun Xu, PhD – Washington University in St. Louis

  Primary Investigator: Matthew R. Bersi, PhD (he/him/his) – Washington University in St. Louis
• 3:30 PM - 4:30 PM EST

  Pericyte Uncoupling and Bridging in Prolonged Hyperglycemia
  

  Presenting Author: Yashasvisai Veeramasu – University of Virginia Biomedical Engineering Department

  Co-Author: Kareem El-Ghazawi – University of Virginia Biomedical Engineering Department

  Co-Author: Anthony C. Bruce, MS – University of Virginia Biomedical Engineering Department

  Primary Investigator: Shayn M. Peirce, PhD (she/her/hers) – University of Virginia
• 3:30 PM - 4:30 PM EST

  Pooled, low-cost synthesis of large-scale T cell receptor libraries
  

  Presenting Author: Rachit Mukkamala (he/him/his) – Massachusetts Institute of Technology

  Co-Author: Stephanie Gaglione – Massachusetts Institute of Technology

  Last Author: Michael Birnbaum, PhD – Massachusetts Institute of Technology
• 3:30 PM - 4:30 PM EST

  Programmable DNA methylation and tunable transcriptional silencing using engineered CRISPR/Cas9-based DNA methyltransferase variants
  

  Presenting Author: Samantha L. Lydon (she/her/hers) – Rice University

  Co-Author: Rosa Selenia Guerra-Resendez, BS (she/her/hers) – Rice University

  Last Author: Isaac Hilton, PhD – Rice University
• 3:30 PM - 4:30 PM EST

  Quantifying Breast Cancer Cellular Morphology and its Link to Metastasis
  

  Presenting Author: Lily B. Watts (she/her/hers) – University of Georgia

  Co-Author: Kyndra Higgins (she/her/hers) – University of Georgia

  Primary Investigator: Cheryl T. Gomillion, Ph. D. (she/her/hers) – University of Georgia
• 3:30 PM - 4:30 PM EST

  Rapid Bacterial Detection in Wastewater via Colorimetric Analysis of Dye-Integrated Copolymer with Machine Learning-Based Quantification
  

  Presenting Author: Manish Rayamajhi (he/him/his) – University of South Dakota

  Co-Author: Tim W. Hartman, MS – University of South Dakota

  Primary Investigator: Dr. Ying Ding, PhD – University of South Dakota

  Co-Author: Venkataramana Gadhamshetty – South Dakota School of Mines & Technology

  Last Author: Etienne Gnimpieba – University of South Dakota
• 3:30 PM - 4:30 PM EST

  Rationally designed tau-specific receptors for spatiotemporally regulated gene and cell therapies against neurodegeneration
  

  Presenting Author: Dylan J. Conger (he/him/his) – Brunger Lab, Department of Biomedical Engineering, Vanderbilt University

  Co-Author: Madeline R. Spetz (she/her/hers) – Brunger lab, Department of Biomedical Engineering, Vanderbilt University

  Co-Author: Lauren E. Drake – Lippmann lab, Department of Chemical and Biomolecular Engineering, Vanderbilt Universtity

  Co-Author: Ethan S. Lippmann, PhD – Vanderbilt University

  Primary Investigator: Jonathan Brunger, PhD – Vanderbilt University
• 3:30 PM - 4:30 PM EST

  Reproducing Nanoparticle Uptake in Artificial Cells Using Droplet Interface Bilayers
  

  Presenting Author: Mira Patel – The University of Mississippi

  Co-Author: Sarita Shrestha – University of Georgia

  Primary Investigator: Eric C. Freeman, PhD – University of Georgia
• 3:30 PM - 4:30 PM EST

  RNA-guided Transcriptional Upregulation of Neuromuscular Disease Modifiers Using CRISPR-DREAM
  

  Presenting Author: Ian Popp (he/him/his) – University of Arkansas

  Primary Investigator: Christopher Nelson, PhD – University of Arkansas

  Co-Author: Eliana Adamos – University of Arkansas Fayetteville
• 3:30 PM - 4:30 PM EST

  Studying the impact of obese adipose tissues on cartilage - a pilot study
  

  Presenting Author: Matthew Murrison – University of Pittsburgh

  Co-Author: Sophie Hines – Department of Bioengineering, University of Pittsburgh Swanson School of Engineering & Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine

  Co-Author: Meagan Makarczyk – Department of Bioengineering, University of Pittsburgh Swanson School of Engineering & Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine

  Primary Investigator: Hang Lin – Department of Bioengineering, University of Pittsburgh Swanson School of Engineering & Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine
• 3:30 PM - 4:30 PM EST

  SUN-KASH Proteins – An Analysis of How They Bind
  

  Presenting Author: Jadel Amaria Estiverne – Inclusion and Innovation in Medical Devices at University of Massachusetts Lowell

  Co-Author: Yanfen Li, PhD (she/her/hers) – University of Massachusetts Lowell

  Co-Author: Marla Hilderbrand-Chae, MA (she/her/hers) – University of Massachusetts Lowell
• 3:30 PM - 4:30 PM EST

  Simulated tumor growth-induced mechanical compression induces epigenetic alternations in glioblastoma models in vitro
  

  Presenting Author: Golnaz Asaadi Tehrani, PhD (she/her/hers) – Notre Dame university

  Co-Author: Becca Kubick – Notre Dame university

  Primary Investigator: Meenal Datta, PhD – University of Notre Dame
• 3:30 PM - 4:30 PM EST

  Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts
  

  Presenting Author: Pratik Kamat, PhD – Johns Hopkins University

  Co-Author: Nico Macaluso – Johns Hopkins University

  Co-Author: Chanhong Min (he/him/his) – Department of Biomedical Engineering, Johns Hopkins University

  Co-Author: Anshika Agrawal – Johns Hopkins University

  Co-Author: Aaron Winston – Johns Hopkins University

  Co-Author: Lauren Pan – Johns Hopkins University

  Co-Author: Bartholomew Starich – Johns Hopkins University

  Co-Author: Pei-Hsun Wu, PhD – Johns Hopkins University

  Co-Author: Jean Fan, PhD – Johns Hopkins University

  Primary Investigator: Jude M. Phillip, PhD (he/him/his) – Department of Biomedical Engineering, Johns Hopkins University

  Co-Author: Jeremy Walston (he/him/his) – Johns Hopkins University
• 3:30 PM - 4:30 PM EST

  Spatial Omic Cellular Taxonomy of Human Hippocampus Reveals Region-Specific Heterogeneity in Proteome, Transcriptome and Epigenome
  

  Presenting Author: Yang Xiao (she/her/hers) – Columbia University

  Co-Author: Graham Su – Yale University

  Co-Author: Yuqi Tan, PhD – Stanford University

  Co-Author: Nima Asaad – Icahn School of Medicine at Mount Sinai

  Co-Author: Yanxiang Deng, PhD – University of Pennsylvania

  Co-Author: Yao Lu, MS – Yale University

  Co-Author: Tianyu Li – Columbia University

  Co-Author: Dongjoo Kim – Yale University

  Co-Author: Gorazd Rosoklija – Columbia University

  Co-Author: archibald enninful – Yale University

  Co-Author: Zhiliang Bai, PhD (he/him/his) – Yale University

  Co-Author: Yang Liu – Yale School of medicine

  Co-Author: Cheick a t Sissoko, MS – University of Cincinnati College of Medicine

  Co-Author: Madeline Mariani, BA – Columbia University

  Co-Author: Tingting Wu – Columbia University

  Co-Author: Phi Nguyen – Columbia University

  Co-Author: Huiyi Liang, PhD (she/her/hers) – Columbia University

  Co-Author: Andrew Dwork – Columbia University

  Co-Author: Rene Hen – Columbia University

  Co-Author: Garry Nolan – Stanford University

  Co-Author: J. John Mann, MD – Columbia University

  Co-Author: Sai Ma – Icahn School of Medicine at Mount Sinai

  Co-Author: Rong Fan – Yale University

  Co-Author: Maura Boldrini – Columbia University

  Last Author: Kam Leong, B.S., Ph.D. – Columbia University
• 3:30 PM - 4:30 PM EST

  Spatial tri-omic mapping of mouse and human brain development and neuroinflammation
  

  Presenting Author: Di Zhang – Yale University

  Primary Investigator: Rong Fan – Yale University
• 3:30 PM - 4:30 PM EST

  Sperm long-distance migration in complex environments
  

  Presenting Author: Meisam Zaferani, PhD – Princeton University

  Co-Author: Christina Kurzthaler – Max Planck Institute for the Physics of Complex Systems

  Last Author: Howard Stone, PhD – Princeton University
• 3:30 PM - 4:30 PM EST

  Substratum stiffness and Yap dynamics regulate differentiation of bipotent alveolar progenitors
  

  Presenting Author: Eric Fowler, PhD – Princeton University

  Primary Investigator: Celeste M. Nelson, PhD (she/her/hers) – Princeton University
• 3:30 PM - 4:30 PM EST

  Synthetic biomolecular condensates enhance translation from a target mRNA in living cells
  

  Presenting Author: Daniel M. Shapiro – Duke University Biomedical Engineering

  Primary Investigator: Ashutosh Chilkoti – Duke University

  Co-Author: Sonal Deshpande

  Co-Author: Ali Eghtesadi
• 3:30 PM - 4:30 PM EST

  Targeted Multiplex CRISPRa Upregulation of ACAN, Col2a1, and Novel Gene, ZNF865, Enhances Cell Infiltration, Cartilage Deposition and Mechanical Properties of Human-sized Engineered Discs
  

  Presenting Author: Hunter Levis, MS – University of Utah

  Co-Author: Matthew Fainor, BS – University of Pennsylvania

  Co-Author: Sarah Gullbrand, PhD – Univeristy of Pennsylvania

  Co-Author: Ameerah Lawal, MS (she/her/hers) – University of Pennsylvania

  Last Author: Robby Bowles – University of Utah
• 3:30 PM - 4:30 PM EST

  The Biochemical Terrain of Tissue Regeneration After Volumetric Muscle Loss: Insights into Pathogenesis and Potential Therapeutic Targets
  

  Presenting Author: Beu P. Oropeza (she/her/hers) – Stanford University

  Co-Author: Ishita Jain, PhD – Stanford University

  Co-Author: Caroline Hu – Stanford University

  Co-Author: Gladys Chiang – Stanford University

  Primary Investigator: Ngan Huang – Stanford University
• 3:30 PM - 4:30 PM EST

  The Electrochemical Functions of Biomolecular Condensates
  

  Co-Author: Wen Yu – Washington University in St. louis

  Co-Author: Yuefeng Ma – Washington University in St. louis

  Co-Author: Xiao Guo – Washington University in St. louis

  Presenting Author: Yifan Dai – Washington University in St. Louis
• 3:30 PM - 4:30 PM EST

  The role of cancer-associated fibroblast-remodeled collagen matrix on monocyte recruitment
  

  Presenting Author: Angela Wong Lau, MS (she/her/hers) – University of Pittsburgh

  Primary Investigator: Ioannis Zervantonakis, PhD (he/him/his) – University of Pittsburgh, Bioengineering
• 3:30 PM - 4:30 PM EST

  Time-lapse Imaging of Keratocyte Morphology in Response to Topography and ECM Composition
  

  Presenting Author: Tarik Shihabeddin (he/him/his) – University of Texas at Dallas

  Primary Investigator: David Schmidtke, PhD – The University of Texas at Dallas
• 3:30 PM - 4:30 PM EST

  Transcriptomics-Driven De Novo Design of Lipid Nanoparticle for RNA Delivery to Disease-Associated Cellular Subtypes
  

  Presenting Author: Lulu Xue, PhD – Bioengineering, School of Engineering and Applied Science, Univeristy of Pennsylvania

  Co-Author: Gan Zhao – Penn Vet School

  Co-Author: Andrew Vaughan – Penn Vet School

  Last Author: Michael J. Mitchell (he/him/his) – Mitchell Lab, University of Pennsylvania
• 3:30 PM - 4:30 PM EST

  Uncovering the effects of fibrotic stiffening on airway epithelial function
  

  Co-Author: Sherry Zhang – Princeton University

  Presenting Author: Evelyn S. Navarro Salazar (she/her/hers) – Princeton University

  Co-Author: Phoebe A. Marshall (she/her/hers) – Princeton University

  Primary Investigator: Celeste M. Nelson, PhD (she/her/hers) – Princeton University
• 3:30 PM - 4:30 PM EST

  Understanding mechanisms and consequences of condensation in oncogeneic receptor tyrosine kinase fusions.
  

  Presenting Author: David Gonzalez-Martinez, M.S. (he/him/his) – University of Pennsylvania

  Co-Author: Thomas Mumford – University of Pennsylvania

  Co-Author: Delaney Wilde – University of Pennsylvania

  Co-Author: Sofia Wissert – University of Pennsylvania

  Primary Investigator: Lukasz Bugaj – University of Pennsylvania
• 3:30 PM - 4:30 PM EST

  Validating microRNA Concentrations in Prostate Cancer Cells to Correlate with Prostate Cancer Stage
  

  Presenting Author: Trisha Patnaik (she/her/hers) – UIUC

  Co-Author: Siva Nalla – UIUC

  Primary Investigator: Andrew Smith – UIUC
• 3:30 PM - 4:30 PM EST

  VEGF-A and PDGFs: Discovery of high-affinity (nanomolar) interactions between cross-family ligand.
  

  Presenting Author: Shobhan Kuila, PHD (he/him/his) – University of Washington

  Co-Author: YINGYE FANG, PhD (she/her/hers) – University of Washington

  Primary Investigator: Princess Imoukhuede, PhD (she/her/hers) – University of Washington
• 3:30 PM - 4:30 PM EST

  Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
  

  Presenting Author: Joshua Graham – Lehigh University Bioengineering

  Co-Author: Jose Castro – Lehigh University

  Co-Author: Lisette Werba – Lehigh University

  Co-Author: Luke Fardone – Lehigh University

  Co-Author: Helen McCarthy – Queens University Belfast

  Last Author: Tomas Gonzalez-Fernandez, PhD – Lehigh University Bioengineering
• 3:30 PM - 4:30 PM EST

  Widespread gene editing in the brain via in utero delivery of mRNA using acid-degradable lipid nanoparticles
  

  Presenting Author: Kewa Gao, MD, PhD (she/her/hers) – University of California, Davis

  Co-Author: Hesong Han – University of California, Berkeley

  Co-Author: Sheng Zhao – University of California, Berkeley

  Co-Author: Matileen Cranick – University of California, Davis

  Co-Author: Shanxiu Xu, MS – University of California, Davis

  Co-Author: Boyan Yin, MA – University of California, Berkeley

  Co-Author: Hengyue Song – University of California, Davis

  Co-Author: Yibo Hu – Central South University

  Co-Author: Jessica Wong (she/her/hers) – University of California, Davis

  Co-Author: Zehua Zhao – University of California, Davis

  Co-Author: Benjamin W. Burgstone (he/him/his) – University of California, Berkeley

  Co-Author: Diana Farmer, MD (she/her/hers) – University of California, Davis

  Co-Author: Niren Murthy – University of California, Berkeley

  Last Author: Aijun Wang, PhD (he/him/his) – University of California, Davis
• 3:30 PM - 4:30 PM EST

  A CATCH supramolecular peptide assembly induces cross presentation in dendritic cells
  

  Presenting Author: Stephen Michel, BS – University of Florida

  Primary Investigator: Benjamin G. Keselowsky – University of Florida

  Last Author: Gregory A. Hudalla, PhD (he/him/his) – University of Florida

  Co-Author: Elias Sayour – University of Florida
• 3:30 PM - 4:30 PM EST

  A Combined Tissue-Engineered, Immunomodulatory, and Rehabilitative Therapy for Volumetric Muscle Loss
  

  Presenting Author: Harper McClain (she/her/hers) – University of Oregon, Phil and Penny Knight Campus for Accelerating Scientific Impact, Wu Tsai Human Performance Alliance

  Primary Investigator: Nick Willett, PhD – University of Oregon - Knight Campus

  Co-Author: Frank Pittmen, MS (he/him/his) – University of Oregon

  Co-Author: Kait Link, DVM – University of Oregon

  Co-Author: Christine Tran, BA – University of Oregon
• 3:30 PM - 4:30 PM EST

  Cadherin Switching and Mesoderm Differentiation Trajectories in Human Embryonic Stem Cells
  

  Presenting Author: Ye Zhu – Rice University

  Primary Investigator: Aryeh Warmflash, PhD – Rice University