Mehrabian Professor
Carngie Mellon University, United States
Yu-li Wang's broad academic experience at institutions of basic science, medicine, and engineering allowed him to collaborate with an unusually wide range of professionals for interdisciplinary research, focusing on cellular mechanical activities. His contributions have catalyzed far-reaching conceptual changes in basic cell biology, regenerative medicine, and engineering. He pioneered live cell imaging in the 1970's using fluorescently tagged proteins and discovered in 1985 the frontal extension mechanism for cell migration. His research in cell division helped convincing the field to focus on the equatorial region for control signals. In late 1990's he introduced tunable, elastic polyacrylamide substrates for detecting and manipulating cellular mechanical interactions, which catalyzed a major transformation of the field of mechanobiology. In addition to the introduction of traction force microscopy, his group discovered the sensitivity of cell growth to material stiffness and the preferential cellular migration toward stiff surfaces termed durotaxis. His recent studies have elucidated the sensitivity of cells to their own size, shape, and migration state. In addition, the discovery of "contact following of locomotion" has filled a major gap about how cell-cell interactions regulate collective behavior. His studies have been described in textbooks and his paper collected in the book “Landmark Papers in Cell Biology”. In addition, the books he edited have served as the defining technical resources for cell imaging and cell mechanics. He has also organized two international conferences and gave lectures internationally in the United States, United Kingdom, Canada, Austria, Germany, France, Sweden, Taiwan, Singapore, and Japan.
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Poster N8 - Sacrificial Electrospun Dipeptide for Encapsulation of Cell Therapies
Friday, October 25, 2024
3:30 PM - 4:30 PM EST