Lipid Nanoparticle-Based mRNA Delivery Systems

Sponsored By 

Session Chair(s)

• 

  John Clegg, PhD (he/him/his)

  Assistant Professor
  University of Oklahoma, Norman
  Norman, Oklahoma, United States
• 

  Chris Bashur, PhD

  Associate Professor
  Florida Institute of Technology
  Melbourne, Florida, United States

Track Chair(s)

• 

  Meenal Datta, PhD

  Assistant Professor
  University of Notre Dame
  South Bend, Indiana, United States
• 

  Jeannine Coburn, PhD

  Associate Professor
  Worcester Polytechnic Institute
  Worcester, Massachusetts, United States

Presentations:

• 2:00 PM – 2:15 PM EST

  Peptide-conjugated lipid nanoparticles for targeted mRNA delivery to brain endothelial and neuronal cells
  

  Presenting Author: Emily L. Han (she/her/hers) – University of Pennsylvania

  Co-Author: Sophia Tang – University of Pennsylvania

  Co-Author: Dongyoon Kim, PhD – University of Pennsylvania

  Co-Author: Amanda M. Murray (she/her/hers) – University of Pennsylvania

  Co-Author: Kelsey L. Swingle, BSE (she/her/hers) – University of Pennsylvania

  Co-Author: Alex G. Hamilton (he/him/his) – University of Pennsylvania

  Co-Author: Marshall S. Padilla, PhD (he/him/his) – University of Pennsylvania

  Co-Author: Jacqueline J. Li, Undergraduate (she/her/hers) – Mitchell Lab, University of Pennsylvania

  Co-Author: Rohan Palanki (he/him/his) – University of Pennsylvania

  Co-Author: Kaitlin Mrksich (she/her/hers) – University of Pennsylvania

  Primary Investigator: Michael J. Mitchell (he/him/his) – Mitchell Lab, University of Pennsylvania
• 2:30 PM – 2:45 PM EST

  Development of Acid-Degradable Lipid Nanoparticles for mRNA Delivery to the Heart
  

  Presenting Author: Tammy Ng (she/her/hers) – University of California, Berkeley

  Co-Author: Gabriel Neiman – University of California, Berkeley

  Co-Author: Ishan Goswami, PhD (he/him/his) – University of California, Berkeley

  Co-Author: Sheng Zhao – University of California, Berkeley

  Co-Author: Hesong Han – University of California, Berkeley

  Co-Author: Dengpan Liang – University of California, Berkeley

  Primary Investigator: Niren Murthy – University of California, Berkeley

  Last Author: Kevin E. Healy – Departments of Bioengineering and Materials Science Engineering, University of California, Berkeley
• 2:45 PM – 3:00 PM EST

  Engineering A Biomaterials-based Lymphoid Niche for mRNA Lipid Nanoparticle Cancer Vaccines
  

  Presenting Author: Yining Zhu, MSE (he/him/his) – Johns Hopkins University

  Co-Author: Zhicheng Yao – Johns Hopkins University

  Co-Author: Shuyi Li – Johns Hopkins University

  Co-Author: Jingyao Ma – Johns Hopkins University

  Co-Author: Christine Wei, BS (she/her/hers) – Johns Hopkins University

  Co-Author: Jessica L. Stelzel – Johns Hopkins University, Biomedical Engineering, Translational Tissue Engineering Center

  Co-Author: Xiaoya Lu, MSE – Johns Hopkins University

  Co-Author: Jinghan Lin – Johns Hopkins University

  Co-Author: Jonathan P. Schneck, MD, PhD (he/him/his) – Johns Hopkins University

  Co-Author: Joshua C. Doloff, MA, PhD (he/him/his) – Johns Hopkins University, Depts. of Biomedical Engineering and Materials Science & Engineering, Translational Tissue Engineering Center (TTEC), and the Institute for NanoBioTechnology (INBT)

  Co-Author: Sashank Reddy – Johns Hopkins University

  Co-Author: John Hickey, PhD – Duke University

  Primary Investigator: Hai-Quan Mao, Hai-Quan Mao, PhD – Johns Hopkins University
• 3:00 PM – 3:15 PM EST

  Insights into mRNA lipid nanoparticle polydispersity and shape of using quantitative solution biophysics
  

  Presenting Author: Marshall S. Padilla, PhD (he/him/his) – University of Pennsylvania

  Co-Author: Sarah Shepherd – RNA NewCo

  Co-Author: Kushol Gupta, PhD (he/him/his) – University of Pennsylvania
• 3:15 PM – 3:30 PM EST

  Lipid nanoparticle optimization for mRNA-based head and neck cancer therapy
  

  Presenting Author: Jacqueline J. Li, Undergraduate (she/her/hers) – Mitchell Lab, University of Pennsylvania

  Co-Author: Marshall S. Padilla, PhD (he/him/his) – University of Pennsylvania

  Co-Author: Qunzhou Zhang (he/him/his) – Department of Oral and Maxillofacial Surgery, Penn Dental Medicine

  Co-Author: Anh D. Le (she/her/hers) – Department of Oral and Maxillofacial Surgery, Penn Dental Medicine

  Primary Investigator: Michael J. Mitchell (he/him/his) – Mitchell Lab, University of Pennsylvania