Epigenetic engineering of cells

Thursday, October 24, 2024

8:30 AM - 10:00 AM EST

Location: Room 350

Moderator(s)

Timothy Downing

Associate Professor
University of California, Irvine
Irvine, California, United States
Song Li, PhD (he/him/his)

Chancellor's Professor
UCLA
Los Angeles, California, United States

Presenting Author(s)

G.V. Shivashankar, PhD

Professor of Mechano-Genomics, Head of Laboratory of Nanoscale Biology
ETH Zurich and Paul Scherrer Institute, Switzerland, United States
Vadim Backman, PhD

McCormick School of Engineering Professor
Northwestern University BME, United States
Ryan Stowers, PhD

Assistant Professor
University of California, Santa Barbara, United States

Session Title for Website and App: Epigenetic engineering of cells

Special Session Program Description: The epigenetic landscape not only determines cell phenotype but also preserves the memory of phenotypic identity, playing a crucial role in cell aging and various diseases. Emerging research reveals that extracellular factors such as matrix composition, control of cell organization, and other biophysical cues from the microenvironment can regulate the epigenetic state through biological signaling (including mechanotransduction) and direct physical deformations of nuclear material like chromatin. However, the underlying mechanisms and their translation into cell engineering applications remain largely unexplored. This symposium seeks to convene both established leaders and rising stars in the field to foster an in-depth discussion on the latest discoveries and challenges. Join us to explore cutting-edge insights and innovative approaches in understanding how extracellular factors influence the epigenetic landscape and its implications for next-generation approaches for cell engineering and disease treatment.

Committee, Sig, or Organization Title: Cellular and Molecular Bioengineering (CMBE)